Paternal age at birth and risk of cancer October 31, 2005 BMC

BMC Cancer. 2005; 5: 143. Published online 2005 October 31. doi: 10.1186/1471-2407-5-143. Copyright © 2005 Choi et al; licensee BioMed Central Ltd. Association of paternal age at birth and the risk of breast cancer in offspring: a case control study Ji-Yeob Choi,1 Kyoung-Mu Lee,1 Sue Kyung Park,1 Dong-Young Noh,2 Sei-Hyun Ahn,3 Keun-Young Yoo,1 and Daehee Kang1,4 1Department of Preventive Medicine, Seoul National University College of Medicine, 28 Yongon-Dong Chongno-Gu, Seoul 110-799 Korea 2Department of General Surgery, Seoul National University College of Medicine, 28 Yongon-Dong Chongno-Gu, Seoul 110-799 Korea 3Department of General Surgery, Ulsan University College of Medicine, 388-1 Pungnap-2dong Songpa-gu, Seoul 138-736, Korea 4Cancer Research Institute, Seoul National University College of Medicine, 28 Yongon-Dong Chongno-Gu, Seoul 110-799 Korea Corresponding author. Ji-Yeob Choi: miso77@snu.ac.kr Kinase proteins control cell division The number of mutated genes that drive the development of cancer is greater than had been thought, research shows.However, as well as these “driver” mutations, each type of cancer cell carries many more “passenger” mutations which play no role in causing disease. The findings, published in Nature, come from the most extensive analysis yet of the human genome and cancer. Sanger Institute scientists looked at more than 500 human genes and 200 types of cancer http://news.bbc.co.uk/2/hi/health/6424117.stm