Archive for April, 2007

Many gene mutations drive Cancer

April 13, 2007

Many gene mutations drive cancer

Cancer protein

Kinase proteins control cell division

The number of mutated genes that drive the development of cancer is greater than had been thought, research shows.However, as well as these “driver” mutations, each type of cancer cell carries many more “passenger” mutations which play no role in causing disease.

The findings, published in Nature, come from the most extensive analysis yet of the human genome and cancer.

Sanger Institute scientists looked at more than 500 human genes and 200 types of cancer.

http://news.bbc.co.uk/2/hi/health/6424117.stm

Paternal age at birth and risk of cancer October 31, 2005 BMC

April 13, 2007

BMC Cancer. 2005; 5: 143.

Published online 2005 October 31. doi: 10.1186/1471-2407-5-143.

Association of paternal age at birth and the risk of breast cancer in offspring: a case control study

Ji-Yeob Choi,1 Kyoung-Mu Lee,1 Sue Kyung Park,1 Dong-Young Noh,2 Sei-Hyun Ahn,3 Keun-Young Yoo,1 and Daehee Kangcorresponding author1,4

1Department of Preventive Medicine, Seoul National University College of Medicine, 28 Yongon-Dong Chongno-Gu, Seoul 110-799 Korea

2Department of General Surgery, Seoul National University College of Medicine, 28 Yongon-Dong Chongno-Gu, Seoul 110-799 Korea

3Department of General Surgery, Ulsan University College of Medicine, 388-1 Pungnap-2dong Songpa-gu, Seoul 138-736, Korea

4Cancer Research Institute, Seoul National University College of Medicine, 28 Yongon-Dong Chongno-Gu, Seoul 110-799 Korea

corresponding authorCorresponding author.

Ji-Yeob Choi: miso77@snu.ac.kr

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